Blog posts from February, 2018

HLA Variants Key to Predicting Kidney Transplant Outcomes

Researchers led by King’s College London’s Graham Lord conducted a genome-wide association study of organ donor and recipient DNA from about 8,000 pairs of donors and recipients. As they reported in the American Journal of Transplantation this week, they replicated known links between the HLA region and outcomes, but were unable to find any genetic link to outcomes outside that region.

“[W]e identified that this area of DNA alone can tell us whether the match between a kidney donor and recipient will work in the long term,” Lord said in a statement. “This has the potential to improve outcomes for transplant patients and deliver treatments that are more personalized to the health needs of individual patients.”

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